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| JOHN JAY COLLEGE OF
CRIMINAL JUSTICE
THE CITY UNIVERSITY OF NEW YORK BIO 315 GENETICS SPRING 2006 |
| Instructor: Dr. Margaret M.
Wallace
Room: 4411 N Tel: (212) 237-8492 |
Tuesday & Thursday 7th period Room: 4105 N
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TEXTS:
Fixsen, W.D. and Lavett, D. (2002).
Solutions manual for modern genetic analysis (2nd
ed.).
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| Course description: BIO 315covers
concepts in modern genetics. Topics
include classical, microbial, and population genetics.
The course emphasizes quantitative analysis and problem solving.
English 102 and BIO 103-104 are the prerequisites.
WEB PAGE: All of the lectures are available as pdf files. Links to all these files can be found on the course web page at http://web.jjay.cuny.edu /~mwallace The pdf files may be downloaded and printed (10 ˘/page) at either the Library or Academic Computing (Rm. 1310). Grades: There will be three (3) lecture exams, each worth 20% of the final grade. There are no make-up exams. If you miss an exam and do not have a valid written excuse, you will receive a score of zero (0%). 20% of your final grade will be derived from the scores on the periodic quizzes. Two five-page papers, worth 10% each, are required.
The relevance of
genetics to clinical medicine (recombinant DNA therapy, cloning) and
forensic science (polymorphisms, population genetics ) will be explored. Students will broaden their knowledge of heredity by exploring relevant genetics sites on the Internet and utilizing the textbook online resources (www.whfreeman.com/mga). Students will hone their problem solving skills through the use of interactive bioinformatics and problem solving tutorials.
The library resources for this course are extensive and include general periodicals such as CQ Researcher, EBSCOhost Academic Search Premier, EBSCOHost Master FILE Premier, and science/forensic science holdings such as General Science Abstracts, InfoTrac Health Reference Center Academic, Science Direct, ACS Journals, PubMed, and the Forensic Bibliographic Database. Attendance: You are required to attend the lectures and to be on time. Lateness in excess of 20 minutes will be counted as an absence. More than two (4) unexcused absences are considered excessive and you will receive a grade of F.
Statement
of the College Policy on Plagiarism: Plagiarism
is the presentation of someone else’s ideas, words,
or artistic, scientific, or technical work as one’s own creation.
Using the ideas or work of another is permissible only when the original
author is identified. Paraphrasing
and summarizing, as well as direct quotations, require citations to the original
source. Plagiarism
may be intentional or unintentional. Lack
of dishonest intent does not necessarily absolve a student of responsibility for
plagiarism. It
is the student’s responsibility to recognize the difference between statements
that are common knowledge (which do not require documentations) and restatements
of the ideas of others. Paraphrase,
summary, and direct quotation are acceptable forms of restatement, as long as
the source is cited. Students who are unsure how and when to provide documentation are advised to consult with their instructors. The library has free guides designed to help students with problems of documentation. The College has officially adopted Turnitin software as a plagiarism prevention tool. Turnitin will be used in this course. Students must personally submit to the instructor in final form a hardcopy of each required paper as well as upload, in a compatible file format, an electronic copy of the paper to Turnitin.com by the specified deadline. Should plagiarism be determined, a grade of zero will be assigned the paper, a course letter grade penalty will be imposed, a ‘PEN’ grade will be assigned, and/or the matter will be referred for formal disciplinary action. The penalty will be dependent on the severity and extent of the offense. If plagiarism is determined based on a Turnitin Originality Report, the student will be permitted to view the report during a faculty/student conference. To avoid such penalties, before submitting a report, ensure it is plagiarism free by including all required references and ensuring all citations are unambiguous. Consult CUNY’s Policy on Academic Integrity for more information. Submitted papers, or parts thereof, that have previously been used for any other course or purpose shall be deemed plagiarized.
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| WEEK | DATE | LECTURE TOPICS | ASSIGNMENTS |
| 1 | JAN 26 | Genetics and the Organism | |
| Structure of Genes and Genomes | |||
| 2 | JAN 31 | Gene Function | |
| FEB 2 | Transmission of DNA at Cell Division | ||
| 3 | FEB 7 | Inheritance of Single-Gene Differences | |
| FEB 9 | |||
| 4 | FEB 14 | Genetic Recombination in Eukaryotes | |
| FEB 16 | |||
| 5 | FEB 23 | Exam 1 Chapters 1-6 | |
| 6 | FEB 28 | Recombination in Bacteria and their | |
| MAR 2 | Viruses | ||
| 7 | MAR 7 | Gene Mutation: Origins and Repair | Ch. 10 p.313-348 |
| MAR 9 | Processes | ||
| 8 | MAR 14 | Chromosome Mutations | Ch. 11 p.349-384 |
| MAR 16 | |||
| 9 | MAR 21 | Mutational Dissection | Ch. 12 p.385-418 |
| MAR 23 | |||
| 10 | MAR 28 | Regulation of Gene Transcription | Ch. 13 p.419-452 |
| MAR 30 | Paper on Genetic Disorders due | ||
| 11 | APR 4 | Review | |
| APR 6 | Exam 2 Chapters 7, 10-13 |
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| 12 | APR 11 | From Gene to Phenotype | Ch. 14 p.453-482 |
| 13 | APR 25 | From Gene to Phenotype cont’d | |
| APR 27 | |||
| 14 | MAY 2 | Recombinant DNA and Genetic | |
| Engineering | |||
| MAY 4 | Genomics | ||
| 15 | MAY 9 | Population Genetics | Ch. 17 p.553-586 |
| MAY 11 | Quantitative Genetics | Ch. 18 p.587-618 | |
| 16 | MAY 16 | Evolutionary Genetics | Ch. 19 p.619-648 |
| Paper on Cloning due | |||
| MAY 25 | Exam 3 Chapters 8-9, 14, 17-19 |