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JOHN JAY COLLEGE OF CRIMINAL JUSTICE

THE CITY UNIVERSITY OF NEW YORK

BIO 315 GENETICS

 SPRING 2006

Instructor: Dr. Margaret M. Wallace

Room: 4411 N

Tel: (212) 237-8492

 

Tuesday & Thursday 7th period

 Room: 4105 N

       

 

 

TEXTS: Griffiths , A.J.F., Gelbart, W.M., Lewontin, R.C., and Miller, J.H., (2002).  Modern genetic analysis (2nd ed.). New York : W. H. Freeman and Company.  

            Fixsen, W.D. and Lavett, D. (2002).  Solutions manual for modern genetic analysis (2nd ed.). New York : W. H. Freeman and Company.

 

 
Course description: BIO 315covers concepts in modern genetics.  Topics include classical, microbial, and population genetics.  The course emphasizes quantitative analysis and problem solving.  English 102 and BIO 103-104 are the prerequisites. 

WEB PAGE: All of the lectures are available as pdf files.  Links to all these files can be found on the course web page at http://web.jjay.cuny.edu /~mwallace  The pdf files may be downloaded and printed (10 ˘/page) at either the Library or Academic Computing (Rm. 1310).

Grades: There will be three (3) lecture exams, each worth 20% of the final grade.  There are no make-up exams.  If you miss an exam and do not have a valid written excuse, you will receive a score of zero (0%).  20% of your final grade will be derived from the scores on the periodic quizzes.  Two five-page papers, worth 10% each, are required. 

 

Knowledge and performance objectives: Students will learn the basic concepts and techniques in the field of modern genetics:
· structure and function of genes and genomes
· patterns of inheritance
· molecular basis of mutations
· genetic engineering techniques

The relevance of genetics to clinical medicine (recombinant DNA therapy, cloning) and forensic science (polymorphisms, population genetics ) will be explored.   

Students will broaden their knowledge of heredity by exploring relevant genetics sites on the Internet and utilizing the textbook online resources (www.whfreeman.com/mga).  Students will hone their problem solving skills through the use of interactive bioinformatics and problem solving tutorials.

 

 

Resources: Students have access to the computers in the Science/Mathematics Learning Center (Rm. 4300 N),  Academic Computing and the Library. 

 
 

The library resources for this course are extensive and include general periodicals such as CQ Researcher, EBSCOhost Academic Search Premier, EBSCOHost Master FILE Premier, and science/forensic science holdings such as General Science Abstracts, InfoTrac Health Reference Center Academic, Science Direct, ACS Journals, PubMed, and the Forensic Bibliographic Database.

 

Attendance: You are required to attend the lectures and to be on time.   Lateness in excess of 20 minutes will be counted as an absence.  More than two (4) unexcused absences are considered excessive and you will receive a grade of F.

 

Statement of the College Policy on Plagiarism:  Plagiarism is the presentation of someone else’s ideas, words, or artistic, scientific, or technical work as one’s own creation.  Using the ideas or work of another is permissible only when the original author is identified.  Paraphrasing and summarizing, as well as direct quotations, require citations to the original source.  

Plagiarism may be intentional or unintentional.  Lack of dishonest intent does not necessarily absolve a student of responsibility for plagiarism.  

It is the student’s responsibility to recognize the difference between statements that are common knowledge (which do not require documentations) and restatements of the ideas of others.  Paraphrase, summary, and direct quotation are acceptable forms of restatement, as long as the source is cited.  

Students who are unsure how and when to provide documentation are advised to consult with their instructors.  The library has free guides designed to help students with problems of documentation.

The College has officially adopted Turnitin software as a plagiarism prevention tool. Turnitin will be used in this course. Students must personally submit to the instructor in final form a hardcopy of each required paper as well as upload, in a compatible file format, an electronic copy of the paper to Turnitin.com by the specified deadline.  Should plagiarism be determined, a grade of zero will be assigned the paper, a course letter grade penalty will be imposed, a ‘PEN’ grade will be assigned, and/or the matter will be referred for formal disciplinary action.  The penalty will be dependent on the severity and extent of the offense. If plagiarism is determined based on a Turnitin Originality Report, the student will be permitted to view the report during a faculty/student conference.  To avoid such penalties, before submitting a report, ensure it is plagiarism free by including all required references and ensuring all citations are unambiguous. Consult CUNY’s Policy on Academic Integrity for more information.  Submitted papers, or parts thereof, that have previously been used for any other course or purpose shall be deemed plagiarized.                 

 

WEEK DATE LECTURE TOPICS ASSIGNMENTS
1 JAN     26 Genetics and the Organism Ch.   1 p.1-22
    Structure of Genes and Genomes Ch.   2 p. 23-54
       
2 JAN   31 Gene Function Ch.   3 p. 55-90
  FEB     2 Transmission of DNA at Cell Division Ch.   4 p. 91-116
       
3 FEB     7 Inheritance of Single-Gene Differences Ch.   5 p.117-146
  FEB     9    
       
4 FEB   14 Genetic Recombination in Eukaryotes Ch.   6 p.147-182
  FEB   16    
       
5 FEB   23 Exam 1 Chapters 1-6  
       
6 FEB    28 Recombination in Bacteria and their  Ch.   7 p.183-212
  MAR    2 Viruses  
       
7 MAR    7 Gene Mutation: Origins and Repair  Ch. 10 p.313-348
  MAR    9 Processes  
       
8 MAR 14 Chromosome Mutations Ch. 11 p.349-384
  MAR 16    
       
9 MAR  21 Mutational Dissection Ch. 12 p.385-418
  MAR  23    
       
10 MAR  28 Regulation of Gene Transcription Ch. 13 p.419-452 
  MAR  30 Paper on Genetic Disorders due  
       
11 APR     4 Review  
  APR     6 Exam 2 Chapters 7, 10-13  
       
12 APR       11 From Gene to Phenotype Ch. 14 p.453-482
       
13 APR      25 From Gene to Phenotype cont’d  
  APR      27    
       
14 MAY   2 Recombinant DNA and Genetic Ch.    8 p.213-264
    Engineering  
  MAY   4 Genomics Ch.    9 p.265-312
       
 15 MAY   9 Population Genetics Ch. 17 p.553-586
  MAY  11 Quantitative Genetics Ch. 18 p.587-618
       
16 MAY  16 Evolutionary Genetics Ch. 19 p.619-648
    Paper on Cloning due  
       
  MAY   25 Exam 3 Chapters 8-9, 14, 17-19