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Henrietta Margolis Nunno, J.D., ph.d.
EDUCATION
Honors: magna cum laude
Order
of the Coif
Class
rank: top 5%
Brooklyn College B.S., Biology, cum
laude, June 1965
BAR
ADMISSION
PROFESSIONAL
EXPERIENCE
8/03-present Assistant Professor, John
Jay College of Criminal Justice, New York, NY
01/02-7/03 Substitute
Assistant Professor,
12/98-8/03 Visiting
Investigator, Science Department (DNA Laboratory),
8/97-6/98 Legal
Intern, Criminal Law Clinic,
Represented
persons charged with misdemeanors from inception of cases through
final
disposition in
1/98-2/98 Participant,
Intensive Trial Advocacy Program (ITAP),
8/96-6/98 Legal
Intern, Innocence Project,
Drafted
motions and briefs regarding reopening of cases and reversal of convictions
using DNA evidence.
10/87-7/95 Research
Associate, Assistant Investigator, Assistant Member, LF Kimball Research
Institute,
Virus Inactivation Laboratory,
3/87-12/87 Visiting
Investigator, Molecular Biology Program, Sloane Kettering Institute for
Cancer
Research,
7/78-3/87 Research
Associate, Assistant Professor, Department of Biology, Brooklyn
College,
Brooklyn, NY; Teaching: General Biology
and “pre-med” Histology
9/72-6/78 Research
and Teaching Fellowships, City University of
6/65-6/68 Research
Assistant, Genetics Laboratory, New York Zoological Society,
New
York, NY (Lab at Museum of Natural History, N.Y., NY)
PROFESSIONAL
ASSOCIATIONS
Legal: American Bar
Association; Association of the Bar of
the City of New York;
New
York State Bar Association.
Scientific: American Association for the Advancement of
Science; New York Academy of
Sciences.
Past Memberships: American
Women in Science; American Society of
Cell Biology; Endocrine
Society;
Gerontological Society of America; American Society
of Zoologists;
American
Society for Photobiology; International Society for Interferon
Research; Society of Sigma Xi.
SELECTED
PATENTS
B. Horowitz, B. Williams, H.
Margolis-Nunno, S. Chin, Inventors. Biological Compositions Containing
Quenchers of Type I and Type II
Photodynamic Reactions. U.S. Patent #
6214534. Issued
.
B. Horowitz, B. Williams, H.
Margolis-Nunno, S. Chin, Inventors. Process for the Sterilization of
Biological
Compositions and the Product Produced Thereby. U.S. Patent # 6087141. Issued 7/11/00.
B. Horowitz, B. Williams, H.
Margolis-Nunno, S. Chin, Inventors. Process for the Sterilization of
Biological
Compositions using Irradiation and Quenchers of Type I and Type II Photodynamic
Reactions. U.S. Patent
# 5981163. Issued 11/19/99.
H. Margolis-Nunno, E.Ben-Hur,
B.Horowitz,
Inventors. Process for the
Sterilization of Biological
Compositions
using UVA1 Irradiation. U.S. Patent #
5789150. Issued 8/4/98.
B. Horowitz, B. Williams, H.
Margolis-Nunno, S. Chin, Inventors. Process for Transfusing
Cell
Containing Fractions Sterilized with Radiation and a Quencher of Type I and
Type II
Photodynamic
Reactions. U.S. Patent # 5712086. Issued 1/27/98.
B. Horowitz, J. Valinsky,
N. Geacintov, B. Williams, S. Rywkin,
H. Nunno, Photodynamic
Inactivation
of Viruses in Cell-Containing Compositions. Patent # 5232884. Issued 8/3/93.
PUBLICATIONS
Margolis-Nunno,
H., Brenner, L., Cascardi, J., Kobilinsky, L. (2001) A new allele of the short
tandem repeat (STR) locus,
CSF1PO. J. Forensic Sci.,
46:208-211.
(This variant posted by HMN 12/99 @
http//www.cstl.nist.gov/div831/strbase)
Margolis-Nunno,
H., Bardossy,
L., Robinson, R., Horowitz B.,
Blachjman, M. (1997)
Psoralen-mediated
photodecontamination of platelet concentrates:
inactivation of cell-free
and cell-associated forms of human
immunodeficiency virus (HIV) and assessment of
platelet function in vivo. Transfusion, 37:889-895.
Margolis-Nunno,
H., Ben-Hur,
E., Gottlieb, P., Robinson, R.,
Oetjen, J.,
Horowitz, B.
(1996) Inactivation by phthalocyanine photosensitization of multiple forms of
human
immunodeficiency virus (HIV) in red
cell concentrates. Transfusion, 36:743-50
.
Gottlieb,
P., Margolis-Nunno, H., Robinson, R.,
Shen, L-G,
Chimezie, E.,
Horowitz, B.,
Ben-Hur,
E. (1996) Inactivation of Trypanosoma cruzi trypomastigote
forms in blood
components with psoralen
and ultraviolet A light. Photochem. Photobiol. 63:
562-65.
Ben-Hur, E., Moor,
A.C.E., Margolis-Nunno, H., Gottlieb, P.,
Zuk, M.M.,
Lustigman, S.,
Van
Steveninck, J.,
Dubbelman, T.M.A.R. (1996) Photodecontamination
of cellular
blood components - Mechanisms and
use of photosensitization in transfusion medicine.
Transfusion Med. Rev. 10:15-22.
Chin, S., Williams, B.,
Gottlieb, P., Margolis-Nunno,
H., Ben-Hur,
E., Hamman,
J., Jin, R.,
Dubovi, E., Horowitz, B. (1995) Virucidal
short wavelength ultraviolet light treatment of
plasma and factor VIII concentrate: protection
of proteins by antioxidants. Blood, 86:4331-4336.
Margolis-Nunno,
H., Robinson, R, Horowitz, B.
Geacintov, N.E., Ben-Hur, E. (1995)
Psoralen-mediated
virus photoinactivation in platelet concentrates:
Enhanced specificity
of virus kill in the absence of
shorter UVA wavelengths. Photochem. and Photobiol.
62:917-922.
Margolis-Nunno,
H., Robinson, R., Ben-Hur, E., Chin, S.,
Orme, T.,
Horowitz, B. (1995)
Elimination
of potential mutagenicity in platelet concentrates
that are virally inactivated with
psoralens
and ultraviolet A light. Transfusion, 35:855-862.
Ben-Hur, E.,
Margolis-Nunno, H., Rywkin, S.,
Horowitz, B. (1995) The use of quenchers
quenchers for enhanced specificity of photosensitized
virus sterilization of blood, In
"Prevention of
Transfusion-Related Infections", F.Sieber, Ed.
CRC Press,
Ben-Hur, E.,
Margolis-Nunno, H., Gottleib, P., Lustigman, S.,
Horowitz, B. (1994)
Photodynamic decontamination of blood
for transfusion. SPIE Vol.2325. Photodynamic
Therapy of Cancer II. D. Brault, G. Jori, J. Moan and E. Ehrenberg, Eds. pp 166-173,
Springer Verlag,
Berlin.
Margolis-Nunno,
H., Robinson , R., Ben-Hur, E., Horowitz, B. (1994) Quencher enhanced
specificity of psoralen
photosensitized virus inactivation in platelet concentrates.
Transfusion, 34:802-810.
Gao, F.,
Margolis-Nunno, H., Williams,
B., Horowitz, B. (1994) Introduction of
solvent/
detergent virus inactivation into preparation
of intravenous immunoglobulins. Shanghai
Medical Journal,
17:18-21.
Horowitz,
B., Prince, A.M., Rywkin, S., Margolis-Nunno, H., Williams, B.,
Geacintov, N.,
Roth, Z., Horowitz, M.S. (1992) Preparation and characterization of virus
sterilized blood
components. Actuar, 20:49-52.
Rywkin, S.,
Lenny, L., Goldstein, J., Geacintov,
N.E., Margolis-Nunno, H., Horowitz, B.
(1992) Importance of Type I and Type II mechanisms
in the photodynamic inactivation of
viruses
in blood with aluminum phthalocyanine
derivatives. Photochem.
Photobiol. 56:
463-469.
Margolis-Nunno, H.,
Williams, B., Rywkin,
S., Geacintov,
N., Horowitz, B. (1992) Virus
sterilization in platelet
concentrates with psoralen and ultraviolet A light in
the presence
of
quenchers. Transfusion 32: 541-547.
Horowitz, B., Rywkin, S., Margolis-Nunno, H., Williams, B.,
Geacintov, N.,
Prince, A.M.,
Pascual,
D., Ragno,
G., Valeri,
CR., Huima-Byron,
T. (1992) Inactivation of viruses in
red
cell and platelet concentrates with aluminum phthalocyanine
(AIPc) sulfonates. Blood
Cells, 18: 141-150.
Schreibman, M.P., Holzman, S., Margolis-Nunno, H. (1991) Maturation and aging of the reproductive
system, In "Vertebrate Endocrinology: Fundamentals and Biomedical Implications." Volume 4, Part A,
Pang, P., Schreibman,
M.P., Eds., Academic Press, NY, pp. 343-378.
Margolis-Nunno, H., Rubin, B.Y.,
Anderson, S.L., Lunn, R.M., Roy,
S.N., Dizik,
M., Sen,
G.C., (1990) Isolation of cDNA clones for the interferon-induced 67,000-dalton
protein:
direct
induction of a family of mRNAs by human interferon-alpha and
interferon-gamma. J.
Interferon Res. 10 : 309-319.
Schreibman, M.P.,
Margolis-Nunno, H. (1989) The brain-pituitary-gonad axis in poikilotherms.
In: "Development, Maturation and Senescence of Neuroendocrine Systems: A Comparative Approach",
Schreibman, M.P., Scanes, C.G., Eds., Academic Press, N.Y., pp.
97-133.
Margolis-Nunno, H., Schreibman,
M.P., Halpern-Sebold,
L. (1987) Sexually dimorphic age-
related
differences in the immunocytochemical distribution of
somatostatin in the platyfish.
Mech.
Ageing Dev. 41: 139-148.
Schreibman, M.P.,
Margolis-Nunno H. (1987)
Reproductive biology of the terminal nerve (nucleus
olfactoretinalis) and other LHRH pathways in teleost fishes. Ann. N Y Acad. Sci.
519: 60-68.
Demski, L.A.,
Fields, R.D., Bullock, T.H., Schreibman,
M.P., Margolis-Nunno, H. (1987) The
terminal
nerve of sharks and rays: Electron microscopic, immunocytochemical
and
electrophysiological
studies. Ann. N Y Acad. Sci. 519:1-32.
Schreibman, M.P.,
Margolis-Nunno, H., Halpern-Sebold, L.(1987)
Aging of the neuroendocrine
system. In: "Hormones and Reproduction in Fish,
Amphibians and Reptiles". Norris,
D.O.,
Jones, R.E., Eds., Plenum Press, NY, pp.
563-584.
Halpern-Sebold, L.R.,
Schreibman, M.P., Margolis-Nunno, H. (1986) Differences between
early-
and late-maturing genotypes of the platyfish (Xiphophorus maculatus) in the
morphometry of their immunoreactive
luteinizing hormone releasing hormone-containing
cells:
a developmental study. J. Exp. Zool . 240: 245-257.
Schreibman, M.P.,
Margolis-Nunno, H., Halpern-Sebold L., Goos H.J., Perlman P.W. (1986) The
influence
of androgen administration on the structure and function of the
brain-pituitary-gonad
axis
of sexually immature platyfish. Cell Tissue Res. 245: 519-524.
Margolis-Nunno, H., Halpern-Sebold,
L., Schreibman,
M.P.(1986) Immunocytochemical
changes
in
serotonin in the forebrain and pituitary of aging fish. Neurobiol. Aging 7:
17-21.
Schreibman, M.P., Margolis-Nunno, H., Halpern-Sebold, L. (1986) The structural and functional
relationship
between olfactory and reproductive systems from birth to old age in fish. In:
"Chemical
Signals in Vertebrates", Duval, D.,
Muller-Schwarze, D. Silverstein, R.M.,
Eds.
Plenum Press, NY, pp. 155-172.
Schreibman, M.P,
Halpern-Sebold, L., Margolis-Nunno, H. (1985) Sexually dimorphic
age-
related
changes in the distribution of immunoreactive luteinizing hormone releasing hormone
in the platyfish. Mech. Ageing Dev. 33 : 29-37.
Halpern-Sebold, L.R.,
Margolis-Kazan, H., Schreibman, M.P., Joh T.H. (1985)
Immunoreactive tyrosine hydroxylase
in the brain and pituitary gland of the platyfish. Proc
Soc.
Exp. Biol. Med. 178 : 486-489.
Margolis-Kazan,
H., Halpern-Sebold,
L.R., Schreibman,
M.P. (1985) Immunocytochemical
localization
of serotonin in the brain and pituitary gland of the platyfish,
Xiphophorus
maculatus. Cell
Tissue Res. 240: 311-314.
Schreibman, M.P.,
Margolis-Kazan, H., Halpern-Sebold, L.,
O'Neill, P.A., Silverman, R.C.
(1984)
Structural and functional links between olfactory and reproductive systems:
puberty-
related
changes in olfactory epithelium. Brain
Res. 302 : 180-183.
Margolis-Kazan,
H., Schreibman,
M.P. (1984) Sexually dimorphic, age-related changes in
pituitary
gonadotropdistribution. Mech. Ageing Dev. 24 : 325-333.
Schreibman, M.P.,
Margolis-Kazan, H., Bloom,
J.L., Kallman,
K.D. (1983) Continued
reproductive potential in aging platyfish as demonstrated by the persistence of gonadotropin,
luteinizing hormone releasing
hormone and spermatogenesis. Mech.
Ageing Dev. 22: 105-112.
Schreibman, M.P.,
Halpern-Sebold, L., Ferin, M., Margolis-Kazan, H., Goos, H.J. (1983)
The
effect of hypophysectomy and gonadotropin
administration on the distribution and
quantity of LH-RH in the brains of platyfish: a combined immunocytochemistry and
radioimmunoassay
study. Brain Res. 267 : 293-300.
Schreibman M.P.,
Margolis-Kazan H., Halpern-Sebold L. (1982) Immunoreactive
gonadotropin
and
luteinizing hormone releasing hormone in the
pituitary gland of neonatal platyfish.Gen.
Comp.
Endocrinol . 47: 385-391.
Schreibman, M.P.,
Pertschuk, L.P., Rainford,
E.A., Margolis-Kazan, H., Gelber, S.J .(1982)
The histochemical
localization of steroid binding sites in the pituitary gland of a teleost
(the
platyfish).
Cell Tissue Res. 226 : 523-530.
Margolis-Kazan,
H., Schreibman,
M.P. (1981) Cross-reactivity between human and fish pituitary
hormones as demonstrated by immunocytochemistry. Cell Tissue Res. 221: 257-267.
Margolis-Kazan,
H., Peute
J., Schreibman,
M.P., Halpern,
L.R. (1981) Ultrastructural
localization
of gonadotropin and luteinizing
hormone releasing hormone in the pituitary
gland
of a teleost fish (the platyfish). J. Exp. Zool. 215 : 99-102.
Schreibman,
M.P., Margolis-Kazan, H. (1979)
The immunocytochemical localization of
gonadotropin, its subunits, and thyrotropin
in the teleost, Xiphophorus
maculatus.. Gen.
Comp.
Endocrinol.
39: 467-474 .
Schreibman, M.P.,
Halpern, L.R.,
Goos, H.J.Th., Margolis-Kazan, H. (1979) Identification of
luteinizing hormone-releasing hormone (LH-RH) in the brain
and pituitary gland of a fish
by
immunocytochemistry.
J.Exp. Zool .
210 153-159.
Margolis-Kazan,
H., Blamire,
J. (1979) Effects of delta9-tetrahydrocannabinol on cytoplasmic
DNA
metabolism and embryogenesis in a somatic cell regenerator mutant of Volvox.
Microbios Letters, 11:7-13.
Margolis-Kazan, H., Blamire J (1979) Effect of tetrahydrocannabinol
and ethidium bromide on
DNA
metabolism and embryogenesis in Volvox. Cytobios, 26: 75-95 .
Margolis-Kazan,
H., Blamire,
J. (1977) The effect of
delta9-tetrahydrocannabinol on cytoplasmic
DNA
metabolism. Biochem.
Biophys. Res. Commun.
76: 674-681.
Margolis-Kazan, H., Blamire J. (1976) The DNA of Volvox carteri: a biophysical and biosynthetic
characterization. Cytobios, 15:
201-216.
PRESENTATIONS AND ABSTRACTS
AMERICAN CHEMICAL SOCIETY (ACS, 2002) Kobilinsky, L., (Presenter) Margolis-Nunno, H., Rothchild,
R.(2002) DNA sequencing establishes a new allele of the short tandem repeat (STR) locus, CSF1PO: its
application in human
identification. Paper number 26
SELECTED
PRESENTATIONS BY HMN AT NATIONAL AND INTERNATIONAL
CONFERENCES (Listed with accompanying abstracts)
AMERICAN SOCIETY FOR PHOTOBIOLOGY (ASP,
1995). Abstract: Margolis-Nunno, H.,
Gottlieb,
P., Ben-Hur,
E., Robinson, R., Horowitz, B. (1995) Photosensitized
inactivation
of multiple forms of HIV in cellular
components of blood. Photochem.
and
Photobiol. 61 (Suppl.) 97S.
AMERICAN SOCIETY FOR PHOTOBIOLOGY (Session
Chair: ASP, 1994) Abstract:
Margolis-Nunno,
H., Ben-Hur,
E., Robinson, R, Horowitz, B. (1994) Psoralen/UVA
treatment
of platelet concentrates: Effect of wavelength on specificity of virus kill.
Blood
84 (Suppl.) 530a.
AMERICAN SOCIETY FOR HEMATOLOGY (ASH,
1994). Abstract: Margolis-Nunno, H.,
Robinson,
R., Ben-Hur,
E., Chin, S., Horowitz, B. (1994) Psoralen removal
follow-
ing virus photoinactivation of
platelet concentrates. Photochem. and Photobiol. 59S :74S.
AMERICAN SOCIETY FOR PHOTOBIOLOGY (ASP, 1993). Abstract: Margolis-Nunno, H.,
Bartley, A., Ben-Hur, E., Huima-Byron, T., MacGregor, H., Robinson, R., Valeri, C.R.,
Horowitz, B. (1993) Quencher mediated protection of platelet integrity during psoralen photoinactivation
of viruses in platelet concentrates.
Blood 82 (Suppl.) 401A.
AMERICAN SOCIETY FOR PHOTOBIOLOGY (ASP, 1993). Abstract: Margolis-Nunno, H., Robinson, R.,
Horowitz, B. (1993) Enhanced psoralen photoinactivation of cell-associated virus in platelet concentrates
with quenchers. Photochem. and Photobiol. 57 (Suppl.) 10S.
INTERNATIONAL SOCIETY FOR THROMBOSIS AND
HAEMOSTASIS (ISTH,
1993).
Presented by HMN. Abstract: Williams, B.,
Margolis-Nunno, H., Rywkin, S.,
Chin,
S., Zou, J., Geacintov, N.,
Horowitz, B.(1993).
Quencher-enhanced
photoinactivation of viruses. Thromb. Haemostas. 69 (6): 943.
AMERICAN SOCIETY FOR PHOTOBIOLOGY (Invited
Symposium Speaker: ASP, 1992):
Abstract: Margolis-Nunno, H., Williams, B.,
Geacintov, N,
Horowitz, B.
(1992) Quencher-enhanced specificity of virus
inactivation with psoralens.
Photochem. and Photobiol., 55 (Suppl.) 113S.
INTERNATIONAL SOCIETY FOR THROMBOSIS AND
HAEMOSTASIS (ISTH, Amsterdam,
Netherlands,
1991). Abstract: Margolis-Nunno, H., Williams,
B., Rywkin,
S., Horowitz, B.(1991) Photochemical virus
sterilization in platelet concentrates
with
psoralen derivatives. Thromb.
Haemostas. 65: 1162.
AMERICAN SOCIETY FOR HEMATOLOGY (ASH, 1991). Abstract: Margolis-Nunno, H., Chin, S.,
Geacintov, N., Williams, B., Horowitz, B.(1991) Virus sterilization of plasma and platelet concentrates:
Enhancement of the specificity of psoralen photoinactivation.
Blood 78 (Suppl.):
352A.
AMERICAN SOCIETY FOR HEMATOLOGY (ASH,
1990). Abstract: Margolis-Nunno, H.,
Rywkin, S., Williams, B.,
Horowitz, B. (1990) Photoinactivation of
viruses
in
platelet concentrates. Blood 76 (Suppl.): 403A.
INTERNATIONAL SOCIETY FOR INTERFERON RESEARCH (ISIR, Florence, Italy, 1989) Abstract:
Margolis-Nunno, H., Rubin, B.Y., Anderson, S.L., Lunn, R.M., Roy, S.N., Dizik, M., Sen, G.C. (1990)
The regulation of the
synthesis of mRNAs encoding the interferon-inducible 67,000 dalton
protein. J. Interferon Res. 9: S230.